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California Moves Closer to Legalizing Certain Psychedelic Drugs with Senate Bill 58

California’s State Assembly has greenlighted Senate Bill 58, a pioneering legislation aiming to legalize the personal possession and use of select natural psychedelic substances for adults aged 21 and above. The bill, championed by San Francisco Democrat Scott Wiener, has undergone revisions in the Assembly following its approval by the Senate earlier this year.

The current version of the bill permits the possession and cultivation of restricted quantities of psilocybin, psilocin, mescaline, and dimethyltryptamine (DMT) – compounds found naturally in certain plants and fungi known for their potential therapeutic benefits in treating mental health disorders like depression and PTSD. Advocates emphasize the significant promise these substances hold in alleviating the nation’s mounting mental health crisis, noting their non-addictive nature and capacity for healing.

The legislation mandates the establishment of a working group under the California Health and Human Services Agency to study the implications of psychedelic use, focusing on safety, efficacy in treating various mental health conditions, and the development of a regulated framework for therapeutic applications. This step signals a progressive move towards recognizing the potential benefits of psychedelics in treating an array of serious mental health conditions, as substantiated by numerous studies and clinical trials.

Senate Bill 58 has garnered substantial support, particularly among mental health clinicians and those struggling with mental health issues who have tried conventional therapies with no success, who see this as a hopeful avenue to access these promising plant-based medicines without criminal repercussions. The bill, which has faced amendments including the establishment of possession limits and the exclusion of synthetic psychedelics like LSD and MDMA, is slated to return to the Senate for approval of the changes before moving to Governor Gavin Newsom’s desk for final endorsement.

The potential passage of this revolutionary bill could signify a watershed moment for psychedelic-assisted therapy clinics in California. As the bill directs the establishment of a structured group to conduct comprehensive studies and propose regulatory frameworks, it could pave the way for clinics to operate within a clearer, legally sanctioned environment. Furthermore, the clinics might witness a surge in demand as individuals seek individual and group therapy options that incorporate these newly legalized substances.

By potentially fostering collaborations with biopharmaceutical entities researching psychedelic compounds, these clinics could become frontiers of innovation, offering advanced, evidence-based treatment modalities for individuals grappling with persistent mental health conditions, thus marking a revolutionary shift in the landscape of mental health care in the state.

The Psychedelica Collective in Beverly Hills is at the forefront of this revolution, offering individual and group ketamine-assisted psychotherapy for those struggling with depression, anxiety, PTSD, and a wide range of other mental health concerns. Call us today for a no-obligation consultation on whether ketamine-assisted therapy is right for you.

Link to full article on Forbes.

Beyond Antidepressants: Four Scientifically-Proven Alternatives to Antidepressants

Why do we need alternatives to antidepressants? Antidepressants, though widely used, have limitations in efficacy, side effects, slow onset, and withdrawal issues. This article explores exercise, and transcranial magnetic stimulation (TMS), psychedelic-assisted therapy, and ketamine therapy as proven alternatives. Discover their benefits and drawbacks, including faster results and fewer side effects. Consider these alternatives to personalize your approach to treating depression.

Why do we need antidepressant alternatives?

Antidepressant medications, like SSRIs and MAOIs, have long been the primary treatment option for people grappling with depression.

While these provide relief for many, they do not work equally well for everyone. 

These are four of the most common reasons why:

  • Limited efficacy and treatment resistance
  • Unwanted side effects
  • Slow onset of action
  • Withdrawal issues and depression relapse

Limited efficacy and treatment resistance

For a significant proportion of patients, antidepressant treatments alone do not lead to substantial improvement.

This is called treatment-resistant depression. It affects up to a third of depressed patients and can be incredibly disheartening.

Treatment resistance occurs due to various factors, such as genetic predispositions, the severity of the depression, or coexisting conditions.

Side effects and tolerability issues

Antidepressants can cause a range of side effects, such as nausea, weight gain or loss, sexual dysfunction, drowsiness, and emotional blunting, to name just a few.

The burden of these side effects can be immense. So, even if someone feels like antidepressants alleviate some of their original symptoms, they may now be faced with new challenges.

Slow onset of action

Traditional antidepressants often take weeks or even months before their full therapeutic effects are realized.

When someone is experiencing acute distress, this slow onset of action is frustrating. The delay in symptom relief can contribute to a sense of hopelessness, driving individuals to seek faster-acting alternatives.

Discontinuation and withdrawal challenges

Even when tapering off gradually, discontinuing antidepressant medication can sometimes lead to antidepressant discontinuation symptoms. Possible withdrawal symptoms include dizziness, headaches, and flu-like sensations, as well as changes in affect, such as low mood, irritability, and anxiety.

Perhaps even more concerning is that individuals who stop taking antidepressants are more likely to experience a depressive relapse – bringing back the original symptoms that led them to take antidepressants in the first place.

4 Scientifically-Proven Alternatives to Antidepressants


In recent years, exercise has gained recognition as a natural remedy for depression, leading more physicians to “prescribe” it as a medicine for depressive symptoms.

While exercise may not be enough for someone with severe depression, for others, it has proven to be just as effective as regular antidepressant medications.

There is often discussion about how high-intensity exercise triggers the release of endorphins, the so-called body’s feel-good chemicals.

However, low-intensity exercise can be just as impactful in its own way as it stimulates the release of brain-derived neurotrophic factors (BDNFs) – proteins that facilitate the growth of nerve cells and the formation of new connections in the brain. This paves the way for new patterns of thoughts and behaviors to be learned and consolidated.

Of course, there is a significant hurdle to overcome here: depression tends to go hand in hand with low motivation and energy.

Even when we feel good, it is at times challenging to get out of bed to exercise on a daily basis. Having to find this willpower when we are depressed can then seem insurmountable.

This is one of the many reasons why the cycle of depression is so hard to break.

Transcranial Magnetic Stimulation (TMS)

Transcranial Magnetic Stimulation is a non-invasive procedure that uses magnetic fields to stimulate specific areas of the brain, typically the prefrontal cortex.

This stimulation is believed to modulate brain activity and restore the balance of neurotransmitters associated with mood regulation. This can lead to a reduction in symptoms such as sadness, hopelessness, and loss of interest.

Unlike traditional antidepressant medications that affect the entire body, TMS specifically targets the brain regions implicated in depression. This localized treatment approach may result in fewer widespread side effects.

While TMS is generally considered safe, there are some downsides to consider.

For one, it may cause scalp discomfort or headache at the site of stimulation. These side effects are usually transient, but more serious ones, like seizures and sudden mood changes, have also been reported. These are considered to be very rare, however.

TMS treatment can also be time-consuming as it typically requires multiple sessions over several weeks, often on an almost daily basis.

Finally, TMS can be a relatively costly treatment, and insurance coverage may vary.

Psychedelic-Assisted Therapy

Psychedelic-assisted therapy involves the controlled use of psychedelic substances in therapeutic settings.

While the exact mechanisms underlying psychedelics’ therapeutic potential remain somewhat of a mystery, one main way through which this may happen is through modulating the activity in the Default Mode Network (DMN) – an interconnected group of brain regions that are thought to contribute to internal modes of cognition used when remembering, thinking about the future, and mind wandering. This temporary alteration is believed to loosen overly rigid, negative patterns of thoughts and behavior that are typically associated with depression.

Like exercise, psychedelics promote neuroplasticity – the brain’s ability to reorganize and strengthen neural connections and form new ones.

Psychedelics can also facilitate therapeutic breakthroughs by provoking spiritual and personal insights, allowing participants to access suppressed emotions and thoughts and gain new perspectives on themselves and their lives.

A controlled and supportive set and setting are essential to ensure one’s safety and well-being, and they are recognized as important factors in producing therapeutic benefits. But for some people with certain underlying vulnerabilities, this might not be enough.

For example, psychedelics may worsen existing symptoms for individuals with severe mental health conditions or those at risk of psychosis.

In others, the substances’ unpredictable nature may lead to adverse reactions, such as anxiety and paranoia.

Ketamine-Assisted Therapy

Ketamine-assisted therapy has gained attention as a potential treatment for depression, with one significant advantage being its rapid onset of action. In contrast to traditional antidepressants, ketamine elicits rapid improvements in mood, often within hours after administration. This is extremely beneficial in cases where immediate treatment is needed, such as cases of suicidal ideation.

Ketamine has also shown particular promise in providing symptom relief in treatment-resistant depression, providing hope for individuals who have not responded to conventional antidepressants. 

Like psychedelics, the exact way in which ketamine provokes its antidepressant effects is yet to be fully known. Nonetheless, the responsible mechanism is likely mediated by ketamine’s effects on glutamate via NMDA receptors in the brain. These receptors are assigned an important role in aspects of synaptic plasticity and memory formation.


In a world where traditional antidepressant medications don’t work equally well for everyone, scientifically-proven alternatives offer new paths to well-being. Some of their benefits include faster results, fewer side effects, and targeted treatment approaches.

As with most things in life, they also have their potential drawbacks, however. These should all be weighed up and carefully considered when thinking about one’s treatment options for depression.

The professionals at the Psychedelica Collective specialize in ketamine-assisted therapy in Los Angeles for a wide range of mental disorders including treatment-resistant depression, PTSD, anxiety, OCD, and many more. For more information or to find out if you are a good candidate for treatment, contact us today to schedule a free 15-min consultation with a clinician.

Promising Effects of LSD-Assisted Therapy on Anxiety in Life-Threatening Illnesses

In a double-blind, placebo-controlled study, researchers investigated the efficacy and safety of LSD-assisted therapy for patients experiencing anxiety, with or without association with a life-threatening illness. The study involved 42 patients receiving either 200 μg of oral LSD or a placebo in two separate sessions. The primary endpoint was anxiety symptoms measured 16 weeks after the last treatment session using the Spielberger State-Trait Anxiety Inventory–Global score. The results showed significant reductions in anxiety scores up to 16 weeks after treatment, as well as reductions in comorbid depression symptoms. Positive acute subjective drug effects and mystical-type experiences correlated with long-term reductions in anxiety symptoms. While mild, transient side effects were reported by 19% of patients, only one serious treatment-related adverse event occurred (acute transient anxiety). Overall, LSD-assisted therapy demonstrated notable and long-lasting reductions in anxiety and depression symptoms.

Like to original study by Holze F. et al can be found here.

Are you or a loved one facing anxiety or depression related to a life-threatening illness? Find hope and healing with Psychedelic-Assisted Therapy in Los Angeles at Psychedelica Collective. Inspired by promising research on LSD-assisted therapy, our experienced team offers compassionate and professional support to help you navigate the challenges of your unique situation.

Don’t let anxiety and depression hold you back – discover the transformative potential of Psychedelic-Assisted Therapy and take the first step towards a brighter, healthier future.

The Need for Professional Psychedelic Therapy: Prioritizing People Over Profit

Recent news of financial struggles and layoffs within psychedelic telehealth companies like Field Trip and Mindbloom highlights the importance of professionally monitored psychedelic-assisted therapy. These companies, which aimed to capitalize on the growing psychedelic industry, have been criticized for their marketing tactics and for providing at-home ketamine therapy services without proper supervision. As the federal Emergency Declaration comes to an end and the Ryan Haight Act of 2008 is set to be enforced again, telehealth companies may no longer be able to prescribe controlled substances like ketamine without in-person consultations.

Professionally guided psychedelic therapy is crucial for helping clients navigate through difficult psychological and emotional experiences, and for integrating these experiences into their lives. The failures of these telehealth companies illustrate the need to prioritize people over profit and promote the human model of healing, rather than replicating the pharmaceutical model.

Original article written by Soul Surgeon can be found here.

For more information on ketamine assisted psychotherapy in Los Angeles, contact the Psychedelica Collective by calling (888) 850-0028 or filling out the form here.

Who is a Good Candidate for Ketamine Assisted Therapy? Exploring the Potential of Ketamine Lozenges in Treating Mental Disorders

Over the past few decades, the demand for novel and more effective mental health treatments has been increasing as conventional treatments are no unable to offer relief to those suffering from treatment resistant disorders. 

One such promising treatment that is gaining significant traction in clinical settings is ketamine assisted psychotherapy. This therapy involves patients taking a dose of sublingual ketamine paired with psychotherapy sessions to facilitate healing and symptom relief. 

While effective, not everyone is a good candidate for this treatment, read on to find out who is a good candidate for ketamine assisted therapy.

Emergence of ketamine in mental health treatment

Research studies and clinical trials

The discovery of ke tamine’s antidepressant effects can be traced back to the 1990s when researchers started investigating its potential use in treating depression. Early studies demonstrated that low doses of ketamine could produce rapid and sustained antidepressant effects in patients with treatment-resistant depression (Berman et al., 2000; Zarate et al., 2006). 

Since then, numerous clinical trials have supported its efficacy in treating other mental health conditions, such as PTSD (Feder et al., 2014) and OCD (Rodriguez et al., 2013).

How ketamine assisted therapy works

Ketamine assisted therapy involves administering doses of ketamine, typically through an intravenous (IV) infusion, intranasal spray, or sublingually in the form of a lozenge in a controlled clinical setting under the supervision of a mental health professional. The ketamine administration is combined with psychotherapy to promote healing of synaptic connections and symptom relief. 

Ketamine is believed to work by blocking the N-methyl-D-aspartate (NMDA) receptor, which plays a crucial role in mood regulation and synaptic plasticity. This action leads to the release of growth factors that promote the formation of new synaptic connections, ultimately enhancing neural plasticity and improving mood (Duman et al., 2016).

The role of a mental health professional

A mental health professional’s (e.g. psychiatrist, therapist) involvement is vital during ketamine assisted therapy to ensure patient safety, monitor the patient’s response to the treatment, and provide therapeutic support throughout the process. The professional may also assist in integrating the patient’s experiences during the ketamine session into their ongoing therapy, helping them gain insights and develop new coping strategies.

The journey

Ketamine assisted therapy typically involves a series of treatment sessions, with the number and frequency of sessions determined by the patient’s needs and response to the therapy. A single session usually lasts for a few hours, including the time needed for ketamine administration, the patient’s experience under the influence of ketamine, and a debriefing period with the mental health professional.

Ketamine Lozenges: A Promising Alternative

What are ketamine lozenges?

Ketamine lozenges are an innovative formulation of ketamine, designed for oral administration. These lozenges contain a lower dose of ketamine compared to intravenous or intranasal administration methods and offer a more convenient and accessible option for patients seeking ketamine assisted therapy.

In a session, the patient places the lozenge under their tongue and let’s it dissolve over the course of 20 minutes to ingest the appropriate dose. As the effects set in, the therapist or guide will navigate the patient through the journey.

Advantages of ketamine lozenges compared to alternatives

At-home administration

One of the main benefits of ketamine lozenges is the potential for at-home administration under the guidance of a mental health professional. This allows patients to receive treatment in the comfort of their own homes, reducing the need for frequent clinic visits and potentially lowering the overall cost of treatment.

Lower doses and side effects

Ketamine lozenges contain a lower dose of ketamine compared to other administration methods, which may result in fewer side effects and a more tolerable experience for patients. 

Additionally, the oral administration allows for a slower absorption of the drug, providing a more gradual and controlled release of ketamine into the bloodstream.

Studies supporting the use of ketamine lozenges

Research on ketamine lozenges is still in its early stages, but preliminary studies have shown promising results. A pilot study by Lara et al. (2013) found that oral ketamine was effective in reducing depressive symptoms in patients with treatment-resistant depression. 

While more extensive research is needed to fully understand the potential of ketamine lozenges in treating mental health disorders, initial findings indicate that they may be a valuable alternative to traditional ketamine assisted therapy.

Identifying Good Candidates for Ketamine Assisted Therapy

Criteria for a good candidate

Treatment-resistant mental health disorders

Ketamine assisted therapy is primarily aimed at individuals suffering from mental health disorders that have not responded to conventional treatments, such as antidepressants or psychotherapy. These patients may have tried multiple treatment approaches without significant improvement in their symptoms, making them ideal candidates for ketamine assisted therapy.

Adequate physical health

Before considering ketamine assisted therapy, it is essential to ensure that a patient is in good physical health. Potential candidates should undergo a thorough medical evaluation, including a review of their medical history and any current medications, to identify any contraindications or potential complications.

Informed consent and realistic expectations

Good candidates for ketamine assisted therapy should be well-informed about the treatment process, its potential benefits and risks, and any possible side effects. They should also have realistic expectations regarding the outcomes of the therapy, understanding that it may not work for everyone and that additional treatment sessions may be required to achieve the desired results.

Mental health disorders that may benefit from ketamine assisted therapy

Major depressive disorder

Research has consistently shown that ketamine assisted therapy can be effective in treating major depressive disorder, particularly in patients who have not responded to traditional treatments.

Post-traumatic stress disorder (PTSD)

Ketamine assisted therapy has also been shown to be effective in alleviating symptoms of PTSD, with some studies reporting rapid and sustained improvements in patients who had not responded to conventional treatments (Feder et al., 2014).

Obsessive-compulsive disorder (OCD)

Preliminary research suggests that ketamine assisted therapy may be beneficial for patients with OCD who have not responded to traditional therapies (Rodriguez et al., 2013).

Other conditions under investigation

Researchers are currently exploring the potential of ketamine assisted therapy in treating other mental health conditions, such as bipolar disorder, generalized anxiety disorder, and substance use disorders. While more research is needed, early findings suggest that ketamine assisted therapy may have broader applications in the field of mental health.

Factors that may exclude someone from ketamine assisted therapy

Certain medical conditions

Individuals with specific medical conditions, such as uncontrolled high blood pressure, heart disease, or a history of seizures, may not be suitable candidates for ketamine assisted therapy due to potential risks and complications.

Other contraindications

Pregnant or breastfeeding individuals and those with a history of severe allergic reactions to ketamine or related medications should avoid ketamine assisted therapy.

Our Ketamine Assisted Therapy Clinic in Los Angeles

Overview of our clinic

State-of-the-art facility

Our ketamine assisted therapy clinic in Los Angeles is a modern, state-of-the-art facility designed to provide the highest level of care to patients seeking relief from treatment-resistant mental health disorders. Our experienced team of mental health professionals and clinicians work closely with patients to develop personalized treatment plans that address their unique needs and circumstances.

Comprehensive care

We offer a comprehensive range of services, including initial consultations, medical evaluations, ketamine infusions, and ketamine lozenge therapy. Our clinic is dedicated to providing safe and effective treatment options for patients struggling with mental health disorders that have not responded to traditional therapies.

Experienced mental health providers

Our team consists of experienced mental health providers, including psychiatrists, and licensed therapists. These professionals have extensive experience and knowledge of ketamine assisted therapy and are dedicated to helping patients find relief from their symptoms.

What to expect during treatment

Thorough assessment

Prior to beginning ketamine assisted therapy, patients undergo a thorough consultation to determine their suitability for treatment. This assessment includes a review of medical history, current medications, and any contraindications to ketamine therapy.

Personalized treatment plans

Our team of professionals works closely with each patient to develop a personalized treatment plan that takes into account their specific needs and goals. Treatment plans may include a combination of ketamine infusions and/or ketamine lozenges, as well as ongoing monitoring and follow-up care.

Comfort and safety

Our clinic prioritizes patient comfort and safety throughout the entire treatment process. We provide a welcoming, supportive environment where patients can relax and focus on their healing journey.

Who is a Good Candidate for Ketamine Assisted Therapy in Los Angeles

Ketamine assisted therapy has emerged as a promising treatment option for individuals suffering from treatment-resistant mental health disorders, including major depressive disorder, post-traumatic stress disorder, and obsessive-compulsive disorder. With its rapid onset of action and the potential for sustained symptom relief, ketamine assisted therapy offers new hope for those struggling with these debilitating conditions.

Our ketamine assisted therapy clinic in Los Angeles is dedicated to providing the highest level of care to patients seeking relief from treatment-resistant mental health disorders. Our state-of-the-art facility, experienced team of professionals, and personalized approach to treatment ensure that our patients receive the support and guidance they need to achieve the best possible outcomes.

If you or a loved one is struggling with a treatment-resistant mental health disorder, we invite you to explore the potential benefits of ketamine assisted therapy at Psychedelica Collective. Contact us today to learn more about our services and schedule a consultation with our team of mental health professionals.

Unveiling the Potential of Psychedelic-Assisted Therapy: A Deep Dive into Treatment and Outcomes

In recent years, the mental health landscape has witnessed a growing demand for innovative and effective treatments. As rates of depression, anxiety, and other mental health disorders continue to climb, the need for novel treatments with less side effects becomes more urgent. 

Imagine a world where previously treatment-resistant mental health conditions can be addressed with newfound hope and success. This is the captivating promise of psychedelic-assisted therapy, a groundbreaking approach that combines age-old wisdom, cutting-edge science, and talk therapy. Join us as we embark on a journey to explore the fascinating interplay between psychedelic therapy, psychedelic drugs, and the treatment of mental disorders. 

Read along as we delve into the potential benefits and challenges of this emerging field of mental health. 

Psychedelic Assisted Therapy: A New Frontier in Mental Health

What is psychedelic assisted therapy

Psychedelic assisted therapy refers to a therapeutic approach that involves the use of psychedelic substances in a controlled and supportive setting to facilitate psychological healing and personal growth. This technique can be traced back to indigenous cultures that have harnessed psychedelic plants in healing rituals for centuries, most notably ayahuasca and psilocybin. 

In the mid-20th century, the advent of synthesized psychedelic substances, such as LSD, sparked a wave of research into their potential therapeutic applications. However, due to political and social factors, this research came to a halt in the 1970s.

The resurgence of psychedelics for mental health treatment

In recent years, there has been a renewed interest in the therapeutic potential of psychedelic substances. This revival is fueled by a combination of factors, including a growing body of scientific evidence, increased public awareness, and the recognition of the limitations of conventional treatments for mental health disorders. 

Several prestigious institutions, led by Johns Hopkins University and Imperial College London, have established dedicated research centers to study the efficacy and safety of psychedelic therapies and establish protocols in the treatment of different mental health disorders.

How does psychedelic assisted therapy work

Psychedelic assisted therapy offers a unique approach to mental health treatment, addressing the root causes of psychological distress rather than merely managing symptoms with medications that come with side effects. By inducing an altered state of consciousness supervised by a trained clinician, psychedelic substances can facilitate profound personal insights, emotional breakthroughs, and a greater sense of connection with oneself and others. 

This can lead to lasting improvements in mental health and well-being. However, it is essential to note that the success of psychedelic therapy is highly dependent on the set (the individual’s mindset) and setting (the therapeutic environment) in which the substances are administered.

Psychedelic Drugs: Key Players in Psychedelic-Assisted Therapy

Overview of the most common psychedelic drugs used in therapy

Psilocybin (magic mushrooms)

A naturally occurring compound found in certain species of mushrooms, psilocybin has been shown to effectively treat depression, anxiety, and addiction in clinical trials. Its effects include altered perceptions, increased introspection, and heightened emotional sensitivity.

Lysergic acid diethylamide (LSD)

A synthetic psychedelic substance, LSD has been researched for its potential in treating a variety of mental health disorders, including anxiety, depression, and PTSD. LSD can induce vivid visual and auditory hallucinations, profound shifts in perception, and increased self-awareness.

MDMA (molly, ecstasy)

Although not a classic psychedelic, MDMA is often included in the context of psychedelic therapy due to its ability to enhance empathy, self-compassion, and emotional openness. It has shown promise in the treatment of PTSD, social anxiety, and other trauma-related disorders.

Ayahuasca (DMT)

A traditional Amazonian plant-based brew, ayahuasca contains the powerful psychedelic compound DMT. It has been studied for its potential to treat addiction, depression, and anxiety. Ayahuasca can induce intense, visionary experiences and deep emotional processing.


Originally developed as an anesthetic, ketamine has emerged as a promising treatment for depression, particularly treatment-resistant depression. It is also used to address anxiety and PTSD. Ketamine can be administered via various routes, including intravenous infusion, intranasal spray, and oral ketamine lozenges. Its effects include dissociation, altered perceptions, and a profound sense of relaxation.

The science behind how psychedelics work in the brain

Psychedelic substances interact with various neurotransmitter systems in the brain, particularly the serotonin system. They often bind to the 5-HT2A serotonin receptor, which plays a crucial role in regulating mood, perception, and cognition. Ketamine, on the other hand, primarily acts on the glutamate system by blocking NMDA receptors. This receptor blockade leads to changes in neural activity and connectivity, allowing for enhanced introspection, emotional processing, and cognitive flexibility. 

These neurobiological effects, when combined with a supportive therapeutic environment, can facilitate lasting psychological change.

Safety and legal status of these substances

While psychedelic substances have a relatively low risk of addiction and are considered physiologically safe when used in controlled settings, they remain classified as illegal substances in many countries. 

However, there has been a shift in recent years, with some jurisdictions decriminalizing or legalizing the use of certain psychedelics for medical and therapeutic purposes. Ketamine, as a legally available medication, can be prescribed by physicians for off-label use in treating mental health disorders. It is essential to stay informed about the legal status of these substances and to only use them under the guidance of trained professionals in a therapeutic context.

Treatment of Mental Disorders with Psychedelic-Assisted Therapy

The role of psychedelic therapy in addressing mental health disorders


Psychedelic-assisted therapy, particularly with psilocybin, ketamine, and MDMA has demonstrated promising results in treating various forms of depression, including treatment-resistant depression. Patients often report reduced symptoms and improved mood following sessions, with some experiencing lasting relief after just a few guided sessions.


Research has shown that psychedelics, such as psilocybin and LSD, can significantly reduce anxiety levels in individuals with life-threatening illnesses, chronic anxiety disorders, and end-of-life. Patients typically experience a shift in perspective and greater emotional resilience after undergoing psychedelic-assisted therapy.

Post-traumatic stress disorder (PTSD)

MDMA-assisted therapy has emerged as a groundbreaking treatment option for individuals with PTSD. By fostering emotional openness and reducing fear, MDMA can help patients process and integrate traumatic memories, leading to significant symptom reduction and improved quality of life.

Obsessive-compulsive disorder (OCD)

Preliminary research suggests that psilocybin and other psychedelics may help alleviate symptoms of OCD by promoting cognitive flexibility and disrupting rigid thought patterns.


Psychedelic-assisted therapy, using substances like psilocybin, ketamine, and ayahuasca, has shown promise in treating various forms of addiction, such as alcohol, nicotine, and opioid dependencies. Patients often report increased self-awareness, a sense of spiritual connectedness, and a shift in priorities that can support lasting recovery.

Clinical trials and research evidence supporting the efficacy of psychedelic-assisted therapy

A growing body of research supports the efficacy of psychedelic-assisted therapy for various mental health disorders. Several randomized controlled trials and observational studies have demonstrated significant improvements in symptoms and overall well-being following psychedelic-assisted therapy. 

While the exact mechanisms underlying these benefits remain an area of ongoing investigation, it is clear that psychedelics, when used in a controlled and supportive environment, can catalyze profound psychological transformations.

A glimpse into a psychedelic-assisted therapy session

Psychedelic-assisted therapy typically involves a preparation stage, the psychedelic experience itself, and an integration phase. During the preparation stage, the therapist and patient build rapport, establish therapeutic goals, and discuss the patient’s intentions for the session. This stage helps create a foundation of trust and safety, setting the stage for a successful therapeutic experience.

On the day of the session, the patient is provided with a comfortable and calm setting, often with dim lighting, soft furnishings, and soothing music. The therapist administers the psychedelic substance, and the patient is encouraged to wear eye shades and focus on their inner experience as the drug takes effect. The therapist remains present throughout the session, providing support, guidance, and reassurance as needed.

During the psychedelic experience, patients may encounter a wide range of emotions, memories, and insights. The therapist helps the patient navigate these experiences, offering encouragement and validation as they process the material that arises. The duration of the session varies depending on the substance used, ranging from a few hours for ketamine to an entire day for substances like psilocybin or LSD.

Following the session, the integration phase begins. This involves discussing the insights and experiences from the psychedelic journey, identifying themes and patterns, and translating them into actionable steps for personal growth and healing. The integration process is essential for ensuring that the benefits of the psychedelic experience are fully realized and incorporated into the patient’s daily life.

The importance of a controlled and supervised environment during treatment

The success of psychedelic-assisted therapy is highly dependent on the set and setting in which the substances are administered. The set refers to the individual’s mindset, including their intentions, expectations, and emotional state. The setting encompasses the therapeutic environment, which should be comfortable, safe, and supportive. Trained professionals, such as therapists or psychiatrists, must be present to guide patients through the experience and help them process any challenging emotions or insights that may arise. This controlled and supervised approach ensures the safety and efficacy of psychedelic-assisted therapy, enabling patients to derive the maximum benefit from their experiences.

Psychedelic Assisted Therapy in Los Angeles

Psychedelic-assisted therapy, with its remarkable potential for treating mental health disorders, is truly revolutionizing the way we approach healing and well-being. At Psychedelica Collective in Los Angeles, we are proud to be part of this exciting movement, providing compassionate and evidence-based care that combines the transformative power of psychedelic substances and psychedelic assisted psychotherapy

Our dedicated team of professionals is devoted to guiding each patient on their unique journey toward self-discovery, growth, and lasting well-being. As we continue to explore and witness the extraordinary therapeutic potential of psychedelics, Psychedelica Collective stands as a leader in the field, helping to reshape the landscape of mental health care one life at a time.